Trisha Staab, Grace McIntyre^, Lu Wang, Joycelyn Radeny^, Lisa Bettcher, Melissa Guillen^, Margaret Peck^, Azia Kalil^, Samantha Bromley^, Daniel Raftery, Jason Chan. The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging. Aging. Under Review

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Brycki JD^, Chen See JR^, Letson GR^, Emlet CS^, Unverdorben LV^, Heibeck NS^, Brislawn CJ, Buonaccorsi VP, Chan JP, Lamendella R. Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging. Microbiol Spectr. 2021 Oct 31;9(2):e0049821. doi: 10.1128/Spectrum.00498-21.

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McIntyre G^, Wright J, Wong HT^, Lamendella R, Chan J. (2021) Effects of FUdR on gene expression in the C. elegans bacterial diet OP50. BMC Res Notes. 2021 May 28;14(1):207. doi: 10.1186/s13104-021-05624-6.

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Chan JP*, Wright JR*, Wong HT^, Ardasheva A^, Brumbaugh J^, McLimans C^ & Lamendella R. (2019) Using Bacterial Transcriptomics to Investigate Targets of Host-Bacterial Interactions in Caenorhabditis elegans. Scientific Reports 9, 5545. SciRep.pdf

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Chan JP, Brown J^, Hark^, Nolan^,  Servello^, Hrobuchak H^, and Staab TA. Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis Elegans. Frontiers in Genetics. Sep 21;8:132. Frontiers Genetics Paper.pdf

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Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D and de Camilli P. (2014) Coupling between endocytosis and sphingosine kinase 1 recruitment. Nat Cell Biol. Jul;16(7):652-62. Nature Cell Bio Paper.pdf

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Chan JP, Staab TA, Wang H, Mazzasette C, Butte Z, Sieburth D. (2013) Polarized Localization of an extrasynaptic M1/3/5 Muscarinic Acetylcholine Receptor in Neuron Cell Bodies Regulates Presynaptic Function in C. elegans.  Journal of Neuroscience 33(35): 14146-14159. JNeurosci-2-GAR3.pdf

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Wang H, Girskis K, Janssen T, Chan JP, Dasgupta K, Knowles JA, Schoofs L, Sieburth D. (2013) Neuropeptide Secreted from a Pacemaker Activates Neurons to Control a Rhythmic Behavior Current Biology 23(9): 746-54. Curr Bio.pdf

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Chan JP and Sieburth D. (2012) Localized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors. The Journal of Neuroscience 32(49): 17909-17920. J Neurosci.pdf

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Chan JP, Hu Z, Sieburth D. (2012) Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release. Genes and Development 26(10): 1070-85. Genes Dev.pdf

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Chan JP, Cordeira J, Calderon G, Iyer LK, Rios M. (2008) Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus.  Molecular and Cellular Neuroscience 39(3): 372-83. MCN.pdf

 

Chan JP*, Unger TJ*, Byrnes J, Rios M.  (2006) Examination of behavioral deficits triggered by targeting Bdnf in fetal or postnatal brains of mice.  Neuroscience 142: 49-58.  Neuroscience.pdf

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* Authors contributed equally to this work

^undergrads